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Recurrence of osteomyelitis by the same bacterial strain is well known. We report three patients with a second episode of osteomyelitis at the same site caused by different strains of bacteria from the original. Formerly infected and altered bone surface might present a region of diminished resistance for a new infection.

Recurrent Osteomyelitis Caused by Infection with Different Bacterial Strains without Obvious Source of Reinfection