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Susceptibilities of 12 clinicalMycobacterium tuberculosis isolates to acidified sodium nitrite (ASN) were compared. The results demonstrate that 8 of the 12 isolates exhibited enhanced survival levels in 1.5 mM ASN compared to levels in medium alone, suggesting that low concentrations of reactive nitrogen intermediates have a hormetic effect onM. tuberculosis in vitro.

Low Concentrations of Nitric Oxide Exert a Hormetic Effect onMycobacterium tuberculosisIn Vitro