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Pleuromutilin was discovered in 1951 from an edible mushroom, Pleurotus mutilus , but it was not until the early 1970s that its potential for use as an antimicrobial was more fully recognized ([2][1]). Tiamulin and valnemulin were developed as semisynthetic pleuromutilins whose antimicrobial

Quality Control Guidelines for Susceptibility Testing of Retapamulin (SB-275833) by Reference and Standardized Methods