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The usefulness of employing Belgian selection criteria before performing nucleic acid amplification techniques (NAT) was evaluated. The results of this study show that for smear-negative patients with an abnormal chest radiology result in the absence of a respiratory tract infection by bacterial pathogens, testing with NAT is of major benefit.

Critical Use of Nucleic Acid Amplification Techniques To Test for Mycobacterium tuberculosis in Respiratory Tract Samples