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Most cases of serogroup C meningococcal disease are caused by the clonal lineages ST-8 and ST-11. The gene encoding the putative restriction-modification system NmeDI is specific to these lineages. We report here a monoclonal antibody directed against the NmeDI endonuclease as a tool for their rapid and spe-cific identification.

journal of clinical microbiology

Identification of the Hypervirulent Lineages of <i>Neisseria meningitidis</i> , the ST-8 and ST-11 Complexes, by Using Monoclonal Antibodies Specific to <i>Nme</i> DI

Identification of the Hypervirulent Lineages of Neisseria meningitidis , the ST-8 and ST-11 Complexes, by Using Monoclonal Antibodies Specific to Nme DI