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Type III secretion genes in Aeromonas salmonicida subsp. salmonicida are located on a large plasmid of approximately 140 kb. Cultivation of this organism at elevated temperatures such as 25 degrees C can, however, result in loss of this plasmid. This is accompanied by a loss of virulence for cultured fish cells.

Type III Secretion Genes in Aeromonas salmonicida subsp. salmonicida Are Located on a Large Thermolabile Virulence Plasmid