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Nucleic acid amplification tests (NAATs) for the detection of Chlamydia trachomatis are routinely used on first-catch urine (FCU) specimens. We analyzed data from a head-to-head comparison of NAATs on female FCU specimens and found that the volume of urine collected could affect test performance.

Volume Effect on Sensitivity of Nucleic Acid Amplification Tests for Detection of Chlamydia trachomatis in Urine Specimens from Females