Open AccessAccurate, Noninvasive Detection of Helicobacter pylori DNA from Stool Samples: Potential Usefulness for Monitoring Treatment
Author(s) -
Anthony P. Shuber,
Jennifer J. Ascaño,
Kevin A. Boynton,
Anastasia Mitchell,
Henry F. Frierson,
Wael ElRifai,
Steven Powell
Publication year - 2002
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.40.1.262-264.2002
Subject(s) - helicobacter pylori , helicobacter infections , medicine , microbiology and biotechnology , biology , virology , gastroenterology
A novel DNA assay demonstrating sensitive and accurate detection of Helicobacter pylori from stool samples is reported. Moreover, in three individuals tested for therapeutic response, the assay showed the disappearance of H. pylori DNA during treatment. Thus, this noninvasive molecular biology-based assay has the potential to be a powerful diagnostic tool given its ability to specifically identify H. pylori DNA.
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