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We classified 100 Enterocytozoon bieneusi isolates into five genotypes by a PCR-restriction fragment length polymorphism method. Type I strains were encountered only in human immunodeficiency virus (HIV)-infected patients, whereas type II strains were more frequently found in non-HIV-infected patients (75 versus 10%, respectively; P &lt; 10(-4)), suggesting differences in the epidemiology of E. bieneusi among these patients.

Evidence of Different Enterocytozoon bieneusi Genotypes in Patients with and without Human Immunodeficiency Virus Infection