Open AccessOXA-163-Producing Klebsiella pneumoniae in Cairo, Egypt, in 2009 and 2010
Author(s) -
Mohammed Abdelaziz,
Celestino Bonura,
Aurora Aléo,
Ramadan A. El-Domany,
Teresa Fasciana,
Caterina Mammina
Publication year - 2012
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.06710-11
Subject(s) - klebsiella pneumoniae , cephalosporin , enterobacteriaceae , klebsiella , microbiology and biotechnology , antibiotic resistance , antibiotics , klebsiella infections , biology , medicine , escherichia coli , gene , genetics
Two genetically unrelated OXA-163-carrying Klebsiella pneumoniae strains were identified from two infection cases in June 2009 and May 2010 in Cairo, Egypt. OXA-163-producing Enterobacteriaceae had been previously reported in Argentina only. Both patients had no history of travel abroad. The emergence of this newly recognized OXA-48-related β-lactamase able to hydrolyze cephalosporins and carbapenems is especially worrying in a geographic area where OXA-48 is endemic and effective surveillance for antibiotic resistance is largely unaffordable.
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