Open AccessMolecular Epidemiology of Clostridium difficile Strains in Children Compared with That of Strains Circulating in Adults with Clostridium difficile-Associated Infection
Author(s) -
Nicole Stoesser,
Derrick W. Crook,
Rowena Fung,
David Griffiths,
Rosalind M. Harding,
Melina Kachrimanidou,
Satish Keshav,
Tim Peto,
Alison Vaughan,
A. Sarah Walker,
Kate E. Dingle
Publication year - 2011
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.05349-11
Subject(s) - clostridium difficile , genotype , clostridiaceae , microbiology and biotechnology , molecular epidemiology , epidemiology , biology , clostridium , ribotyping , transmission (telecommunications) , clostridiales , virology , medicine , bacteria , antibiotics , gene , genetics , toxin , electrical engineering , engineering
Molecular analysis of Clostridium difficile (28 isolates) from children (n = 128) in Oxfordshire, United Kingdom, identified eight toxigenic genotypes. Six of these were isolated from 27% of concurrent adult C. difficile-associated infections studied (n = 83). No children carried hypervirulent PCR ribotype 027. Children could participate in the transmission of some adult disease-causing genotypes.
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