Open AccessRapid Detection of β-Lactamase-Hydrolyzing Extended-Spectrum Cephalosporins in Enterobacteriaceae by Use of the New Chromogenic βLacta Test
Author(s) -
María Isabel Morosini,
María García-Castillo,
Marta Tato,
Desirée Gijón,
Aránzazu Valverde,
Patricia Ruíz-Garbajosa,
Rafael Cantón
Publication year - 2014
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.03614-13
Subject(s) - chromogenic , cephalosporin , enterobacteriaceae , microbiology and biotechnology , plasmid , chemistry , biology , escherichia coli , chromatography , antibiotics , biochemistry , gene
The chromogenic βLacta test developed for the rapid detection of β-lactamase-hydrolyzing extended-spectrum cephalosporins inEnterobacteriaceae revealed good performance with extended-spectrum β-lactamase (ESBL) producers (97.5% true-positive results). However, false-negative results occurred with chromosomal AmpC hyperproducers and plasmid AmpC producers, whereas uninterpretable results were mostly due to VIM-1 carbapenemase producers and possibly low levels of expressed ESBLs.
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