Extremely Drug-Resistant Salmonella enterica Serovar Senftenberg Infections in Patients in Zambia
Author(s) -
René S. Hendriksen,
Katrine Joensen,
Chileshe LukwesaMusyani,
Annie Kalonda,
Pimlapas Leekitcharoenphon,
Ruth Nakazwe,
Frank M. Aarestrup,
Henrik Hasman,
James Mwansa
Publication year - 2012
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.02227-12
Subject(s) - salmonella enterica , serotype , microbiology and biotechnology , biology , cephalosporin , virology , salmonella , drug resistance , replicon , plasmid , gene , antibiotics , bacteria , genetics
Two cases of extremely drug-resistant Salmonella enterica serovar Senftenberg isolated from patients in Zambia were investigated by utilizing MIC determinations and whole-genome sequencing. The isolates were resistant to, and harbored genes toward, nine drug classes, including fluoroquinolones and extended-spectrum cephalosporins, contained two plasmid replicons, and differed by 93 single-nucleotide polymorphisms.
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