Open AccessHuman-to-Human Transmission of Tuberculosis Caused by Mycobacterium bovis in Immunocompetent Patients
Author(s) -
Shyam Sunder,
Philippe Lanotte,
Sylvain Godreuil,
Christian Martin,
María-Laura Boschiroli,
Jean-Marc Besnier
Publication year - 2009
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.02042-08
Subject(s) - mycobacterium bovis , biology , mycobacterium tuberculosis , tuberculosis , transmission (telecommunications) , virology , tandem repeat , mycobacterium , microbiology and biotechnology , bovine tuberculosis , genetics , bacteria , medicine , pathology , gene , genome , electrical engineering , engineering
Human-to-human transmissionof Mycobacterium bovis in two immunocompetent patients from the same family was confirmed by spoligotyping (pattern F35, which was only observed in cattle from the same area in France). A single allelic difference between animal and human isolates was observed with mycobacterial interspersed repetitive units containing variable-number tandem repeats, suggesting a jump across the species barrier.