Open AccessVibrio vulnificus DNA Load and Mortality
Author(s) -
DongMin Kim,
SookIn Jung,
HeeChang Jang,
Chang Seop Lee,
Sun Hee Lee,
Na Ra Yun,
Ganesh Prasad Neupane,
KyungHwa Park
Publication year - 2010
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.01913-09
Subject(s) - vibrio vulnificus , vibrionaceae , microbiology and biotechnology , biology , polymerase chain reaction , vibrio infections , medicine , bacteria , genetics , gene
We determined the association between DNA load and mortality in patients withVibrio vulnificus infection. Real-time PCR performed on sera of 27 culture-positive patients showed a significantly higher median DNA load in nonsurvivors than in survivors. Hence, real-time PCR can be used as an early prognostic factor inV. vulnificus septicemia.
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