Open AccessCoinfection of Leptomonas seymouri and Leishmania donovani in Indian Leishmaniasis
Author(s) -
Susmita Ghosh,
Priyanka Banerjee,
Avijit Sarkar,
Simanti Datta,
Mitali Chatterjee
Publication year - 2012
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.00966-12
Subject(s) - leishmania donovani , visceral leishmaniasis , biology , leishmaniasis , coinfection , restriction fragment length polymorphism , virology , internal transcribed spacer , leishmania , microbiology and biotechnology , genetics , polymerase chain reaction , parasite hosting , gene , human immunodeficiency virus (hiv) , ribosomal rna , computer science , world wide web
Leishmania donovani is considered the causative organism of visceral leishmaniasis (VL) and post-kala-azar dermal leishmaniasis (PKDL). Testing of 4/29 DNA samples from VL and PKDL patients as well as 2/7 field isolates showed an aberrant internal transcribed spacer 1 (ITS1) restriction fragment length polymorphism (RFLP) pattern, which upon sequencing strongly matched Leptomonas seymouri, thus confirming its presence in Indian leishmaniasis.
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