Open AccessImpact of Fragmentation on Commutability of Epstein-Barr Virus and Cytomegalovirus Quantitative Standards
Author(s) -
Randall T. Hayden,
Li Tang,
Yin Su,
Linda Cook,
Z. Gu,
Keith R. Jerome,
Jerry Boonyaratanakornkit,
Soya S. Sam,
Stanley Pounds,
Angela M. Caliendo
Publication year - 2019
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.00888-19
Subject(s) - cytomegalovirus , virology , fragmentation (computing) , cytomegalovirus infections , virus , human cytomegalovirus , herpesviridae , biology , viral disease , ecology
Despite the adaptation of international standards, quantitative viral load testing of transplant-associated viruses continues to be limited by interlaboratory disagreement. Studies have suggested that this disagreement and the poor commutability of standards may, in some cases, be linked to amplicon size and the fragmentation of circulating viral DNA.
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