Open AccessEvaluation of the Cavidi ExaVir Load Assay (Version 3) for Plasma Human Immunodeficiency Virus Type 1 Load Monitoring
Author(s) -
Vicki Greengrass,
Megan M. Plate,
Pauline M. Steele,
Justin T. Denholm,
Catherine L. Cherry,
Lisa Morris,
Anna C. Hearps,
Suzanne Crowe
Publication year - 2009
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.00805-09
Subject(s) - viral load , reverse transcriptase , virology , human immunodeficiency virus (hiv) , virus , virus quantification , biology , lentivirus , microbiology and biotechnology , viral disease , polymerase chain reaction , biochemistry , gene
We evaluated the new low-cost ExaVir Load (version 3) reverse transcriptase viral load assay against the Roche Cobas Amplicor assay. Results for samples tested using the reverse transcriptase assay correlated well with those obtained with the Roche assay (r = 0.85;n = 202). The version 3 reverse transcriptase assay shows improved sensitivity compared to the previous version.