Open AccessFiner Snapshot of Circulating Mycobacterium tuberculosis Genotypes in Guadeloupe, Martinique, and French Guiana
Author(s) -
Julie Millet,
William Laurent,
Thierry Zozio,
Nalin Rastogi
Publication year - 2011
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.00708-11
Subject(s) - martinique , locus (genetics) , genotype , tuberculosis , mycobacterium tuberculosis , biology , typing , virology , allele , genetics , west indies , medicine , ethnology , gene , pathology , history
This study shows the benefit of spoligotyping coupled to mycobacterial interspersed repetitive-unit (MIRU) typing to pinpoint circulating Mycobacterium tuberculosis genotypes in Guadeloupe, Martinique, and French Guiana. We hereby propose reduced 4-locus and 6-locus subsets for LAM and Haarlem lineage strains that predominate in South America and the Caribbean, retaining 99.35% and 99.64% of the total discriminatory power of the 12-locus scheme, respectively.
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