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We used multilocus PCR and electrospray ionization mass spectrometry (PCR/ESI-MS) to determine the genotype and drug resistance profiles for 96 Mycobacterium tuberculosis isolates circulating in regions of high and low tuberculosis (TB) endemicity in China. The dominant principal genetic group (PGG) circulating in China was PGG1, and drug-resistant gene mutations were more diversified in the region of low rather than high TB endemicity.

journal of clinical microbiology

Molecular Characterization of Drug-Resistant <i>Mycobacterium tuberculosis</i> Isolates Circulating in China by Multilocus PCR and Electrospray Ionization Mass Spectrometry

Molecular Characterization of Drug-Resistant Mycobacterium tuberculosis Isolates Circulating in China by Multilocus PCR and Electrospray Ionization Mass Spectrometry