Open AccessDroplet Digital PCR-Based Detection of Clarithromycin Resistance in Helicobacter pylori Isolates Reveals Frequent Heteroresistance
Author(s) -
Lu Sun,
Sarah Talarico,
Lena Yao,
Lihua He,
Steve Self,
Yuanhai You,
Huifang Zhang,
Yiyao Zhang,
Yongjun Guo,
Guodong Liu,
Nina R. Salama,
Jianzhong Zhang
Publication year - 2018
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.00019-18
Subject(s) - helicobacter pylori , clarithromycin , microbiology and biotechnology , helicobacter infections , digital polymerase chain reaction , biology , polymerase chain reaction , virology , antibiotics , genetics , gene
Chronic infection withHelicobacter pylori causes peptic ulcers and stomach cancer in a subset of infected individuals. While standard eradication therapy includes multiple antibiotics, treatment failure due to resistance is an increasing clinical problem.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom