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Purified suspensions of meningopneumonitis can be separated on potassium tartrate gradient into populations which are 80 to 90% large particles and those which are 90% small particles. Examination of the tetrazole reduction of both particle types indicates that the small particle has associated with it all of the enzymatic activity of the preparation; it also has associated with it most of the infectivity as well.

Use of Tetrazolium Salts for Electron Transport Studies in Meningopneumonitis III. Separation and Examination of Large and Small Particles