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Falkow, Stanley (Walter Reed Army Institute of Research, Washington, D.C.), J. A. Wohlhieter, R. V. Citarella, and L. S. Baron. Transfer of episomic elements to Proteus. II. Nature of lac(+)Proteus strains isolated from clinical specimens. J. Bacteriol. 88:1598-1601. 1964.-Strains of Proteus mirabilis exhibiting the unusual property of utilizing lactose (lac(+)) have been reported in clinical material. A genetic examination discloses that the lac(+) determinants in these Proteus strains are associated with an infectious element, P, which is distinct from the sex factor of Escherichia coli K-12. The composite genetic element, P-lac, is readily transmissible to other enteric species and possesses properties which conform to those of an episomic element of the transfer variety. CsCl density-gradient studies of deoxyribonucleic acid (DNA) extracted from lac(+)P. mirabilis indicate that the P-lac(+) element did not arise in this species, but was acquired from an organism possessing a markedly different DNA base composition.

journal of bacteriology

TRANSFER OF EPISOMIC ELEMENTS TO PROTEUS II. <scp> Nature of lac + Proteus Strains Isolated From Clinical Specimens </scp>

TRANSFER OF EPISOMIC ELEMENTS TO PROTEUS II. Nature of lac + Proteus Strains Isolated From Clinical Specimens

TRANSFER OF EPISOMIC ELEMENTS TO PROTEUS II. Nature of lac ⁺ Proteus Strains Isolated From Clinical Specimens