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Shepard (1955; 1957a,b; 1958a,b) found differences in the growth rate and pattern of mycobacterial strains in HeLa cells. Our first interest was in the use of human monocytes in measuring virulence of Mlycobacterium tuberculosis and other mycobacteria associated with pulmonary disease. As a part of this study, the trial of an established line of monocytes appeared indicated. This paper is a report of observations made on the intracellular growth of tuberele bacilli and other mycobacterial strains in the J-111 cell line of leukemic monocytes (Osgood and Brooke, 1955).

INTRACELLULAR GROWTH OF TUBERCLE BACILLI AND OTHER MYCOBACTERIA IN THE J-111 CELL LINE OF LEUKEMIC MONOCYTES