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Two p-aminobenzoic acid-resistant mutants of the Madrid E strain of Rickettsia prowazekii, pr and prr have been described in previous publications (Weiss et al., 1957; 1959). It has been shown that certain properties, such as antigenic specificity, infectivity, and virulence for the chick embryo and cotton rat, have not changed in these strains. However, when the study was extended to susceptibility to compounds chemically related to p-aminobenzoic acid, new characteristics were detected. These characteristics are described in this paper.'

INHIBITION BY ACETYLSALICYLIC ACID OF RICKETTSIAL STRAINS RESISTANT TOp-AMINOBENZOIC ACID