English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Recent years have brought a better understanding of the relationships between such seemingly diverse phenomena as formation of protoplasts, the antibacterial action of penicillin, and L-type or pleuropneumonialike type of growth. All these phenomena appear to involve a common mechanism, impairment in the synthesis of the bacterial cell wall. In view of the highly hypertoniic condition inside the organism, loss of the cell wall or decrease in its rigidity would be expected to result in burgeoning of the cell into a sphere and bursting, unless the hypertonicity of the surrounding medium were appropriately increased or the remaining cell envelope retained enough strength to confine the expanded and thus diluted protoplasm. The literature describing morphological changes in bacteria which can be ascribed to the mechanism outlined above is enormous and dates back to the last century. This subject has been reviewed in the recent essay of Lederberg and St. Clair (1958). The dysmorphic effect of LiCl on bacteria which is evaluated in the present study, was described very early by Gamaleia (1900), whose work represents a comprehensive study of the morphological and chemical basis of this phenomenon. Diverse interpretations of these anomalous forms described as Pettenkoferie were reviewed by Kuhn and Sternberg (1931), and by Seppilli and Tolentino (1938). Recently, Pitzurra (1955) and Pitzurra and Mori (1957) reinvestigated the effect of lithium ions on Escherichia coli and compared it with the "protoplasting" effect of penicillin (Pitzurra, 1956). The present study was motivated by a desire to evaluate quantitatively certain properties of

FORMATION AND MULTIPLICATION OF SPHEROPLASTS OF ESCHERICHIA COLI IN THE PRESENCE OF LITHIUM CHLORIDE