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Among the recent reviews on the influence of nutrition on infectious disease, those by Aycock and Lutman (1944), Cannon (1950), and Clark (1950) in special phases of the field and those by McHenry and Leeson (1947), Keys (1949), and Keys et al. (1950) in the broader aspects should be mentioned. Other reports from this laboratory (Kearney et al., 1948; Pond et al., 1952) have described the modifying effect of amino acid deficiencies on the course of Theiler's GDVII encephalomyelitis in mice. Deficiencies of essential amino acids, especially tryptophan, isoleucine, valine, and methionine, result in a prolongation of incubation periods and a reduced incidence of paralytic disease analogous to that observed both with Lansing poliomyelitis and GDVII encephalomyelitis in mice suffering from other nutritional deficiencies (Foster et al., 1944a, b; Rasmussen et al., 1944; and Lichstein et al., 1944, 1945). Similar studies have now been completed with deficiencies of 9 essential amino acids and Lansing poliomyelitis in mice.

THE EFFECT OF CERTAIN AMINO ACID DEFICIENCIES ON LANSING POLIOMYELITIS IN MICE