English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

The literature is replete with instances demonstrating that an increase in the resistance of a strain of micro6rganisms to a toxic substance is an adaptation which is frequently attained when successive generations of that strain are subjected to the influence of sublethal or subinhibitory quantities of the toxic substance. Workers in the early days of specific chemotherapy were lead to postulate the development of drug-fastness in the organisms under study. This conception was first clearly formulated by Mesnil and Nicolle (1906). Ehrlich (1907a, 1907b, 1907c, and 1907d) and his co-workers and Browning (1907, 1908) were the first to demonstrate that the drug-fast character in trypanosomes may be retained in serial animal passages. Uhlenhuth, Hubener and Woithe (1907) were unable to demonstrate this transmissibility in durine infections treated with atoxyl. Mesnil and Brimont (1908a) and Plimmer and Bateman (1908) met with like failure in the treatment of experimental nagana with tartar emetic. The trmissibility of the drug-fast character in tivo is, nevertheless, a general rule. Plimmer and Thomson (1907) encountered it in the treatment of experimental surra and nagana with

journal of bacteriology

Comparative Studies on the Natural and Acquired Resistance of Certain Strains of <i>Escherichia Coli</i> to the Bacteriostatic and Germicidal Effects of Cations

Comparative Studies on the Natural and Acquired Resistance of Certain Strains of Escherichia Coli to the Bacteriostatic and Germicidal Effects of Cations