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We have shown previously that a gene encoding a homologue to the eukaryotic dolichol-phosphate-D-mannose, protein O-D-mannosyltransferase, was required for (phi)C31 infection of Streptomyces coelicolor. Here we show that a gene encoding the homologue to dolichol-phosphate-mannose synthase is also essential for phage sensitivity. These data confirm the role of glycosylation in the phage receptor for (phi)C31 in S. coelicolor.

journal of bacteriology

A Gene Encoding a Homologue of Dolichol Phosphate-β- <scp>d</scp> -Mannose Synthase Is Required for Infection of <i>Streptomyces coelicolor</i> A3(2) by Phage φC31

A Gene Encoding a Homologue of Dolichol Phosphate-β- d -Mannose Synthase Is Required for Infection of Streptomyces coelicolor A3(2) by Phage φC31