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Intracellular hydrogen peroxide is regulated inEscherichia coli by OxyR in response to the metabolic production of H2 O2 . Here, we show that the untranslatedoxyS RNA controlled by OxyR has a role in this regulation. TheoxyS transcript appears to affect the metabolic output of H2 O2 rather than the removal of H2 O2 by catalases-hydroperoxidases.

Role for the oxyS Gene in Regulation of Intracellular Hydrogen Peroxide in Escherichia coli