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FlhD is a positive regulator of cadA. A mutant with a transposon-mediated lacZ fusion to cadA exhibited a cell division phenotype similar to that of the flhD mutant and had FlhD-dependent beta-galactosidase activity. Under different growth conditions, the cell division rate correlated with the level of expression of cadA.

The Escherichia coli flagellar transcriptional activator flhD regulates cell division through induction of the acid response gene cadA