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The Escherichia coli lytB gene, which is involved in penicillin tolerance and control of the stringent response, was identified as a previously described open reading frame designated orf316 located in the ileS-lsp operon (0.4 min on the linkage map).

Identification of the Escherichia coli lytB Gene, Which Is Involved in Penicillin Tolerance and Control of the Stringent Response