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Ribonuclease II action on polyuridylate is competitively inhibited by transfer ribonucleic acid and noncompetitively inhibited by sodium ions. At low substrate levels, adenosine-5'-triphosphate is also inhibitory.

Inhibition of Ribonuclease II of Escherichia coli by Sodium Ions, Adenosine-5′-Triphosphate, and Transfer Ribonucleic Acid