Open AccessIntraspecies Signaling Involving the Diffusible Signal Factor BDSF ( cis -2-Dodecenoic Acid) Influences Virulence in Burkholderia cenocepacia
Author(s) -
Robert P. Ryan,
Yvonne McCarthy,
Steven Alexander Watt,
Karsten Niehaus,
J. Maxwell Dow
Publication year - 2009
Publication title -
journal of bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.652
H-Index - 246
eISSN - 1067-8832
pISSN - 0021-9193
DOI - 10.1128/jb.00473-09
Subject(s) - burkholderia cenocepacia , biology , virulence , virulence factor , microbiology and biotechnology , pathogen , signal transduction , burkholderia , bacteria , genetics , gene
Burkholderia cenocepacia produces a diffusible fatty acid signal molecule,cis -2-dodecenoic acid (BDSF), that has been implicated in interspecies and interkingdom communication. Here, we show that BDSF also acts as an intraspecies signal inB. cenocepacia to control factors contributing to virulence of this major opportunistic pathogen.
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