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The icsP promoter of Shigella spp. is repressed by H-NS and derepressed by VirB. Here, we show that an inverted repeat located between positions -1144 and -1130 relative to the icsP transcription start site is necessary for VirB-dependent derepression. The atypical location of this cis-acting site is discussed.

journal of bacteriology

VirB Alleviates H-NS Repression of the <i>icsP</i> Promoter in <i>Shigella flexneri</i> from Sites More Than One Kilobase Upstream of the Transcription Start Site

VirB Alleviates H-NS Repression of the icsP Promoter in Shigella flexneri from Sites More Than One Kilobase Upstream of the Transcription Start Site