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Deoxyribonucleic acid (DNA) base composition, as measured by guanine plus cytosine (G + C) content, was determined in 17 strains ofSporothrix schenckii andCeratocystis species. The average G + C content forS. schenckii was 54.7 ± 0.2 mol%. No strain ofCeratocystis , with the exception ofC. minor , gave values for G + C content similar to those obtained forS. schenckii . All DNA samples from strains ofS. schenckii cross-hybridized with high percentages of relative binding. DNA samples fromC. stenoceras andC. pilifera showed low degrees of homology withS. schenckii DNA. The DNA fromC. minor hybridized with 75% binding with that from a strain ofS. schenckii , as compared with the homologous reaction.

Deoxyribonucleic Acid Base Composition and Hybridization Studies on the Human Pathogen Sporothrix schenckii and Ceratocystis Species