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The present study showed that incorporation of CpG adjuvant into plasmid DNA coding for NcGRA7 antigen resulted in a twofold increase in the level of protection against congenital transfer of Neospora caninum. The level of protection was considerably higher than that observed in pups born from dams immunized with nonrecombinant plasmid.

Inclusion of CpG Adjuvant with Plasmid DNA Coding for NcGRA7 Improves Protection against Congenital Neosporosis