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We identifiedlbpB , encoding the lipoprotein component of the meningococcal lactoferrin receptor. An LbpB mutant was unable to acquire Fe from lactoferrin and exhibits decreased surface binding to lactoferrin. Primer extension and reverse transcription-PCR analysis indicate thatlbpB andlbpA are cotranscribed on a polycistronic Fe-repressible mRNA.

Identification and Molecular Analysis oflbpBA, Which Encodes the Two-Component Meningococcal Lactoferrin Receptor