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The properties of the immunochemically distinct substances isolated from four strains ofClostridium perfringens , mucoid variants of Hobbs 1, 5, 9, and 10, were shown to be compatible with the hypothesis that polysaccharides are generally responsible for the “type-specificity” of these organisms. The presence of “group-specific” substance was demonstrated by the cross-reaction of recent preparations of Hobbs 5 antisera with the isolated polysaccharides. The cross-reactions were not observed with specific antisera of the other strains studied and were independent of the “type-specific” phenomenon.

Immunochemistry of the Capsular Polysaccharides from Clostridium perfringens: Selected Hobbs Strains 1, 5, 9, and 10