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Pneumocystis carinii was tightly attached to host alveolar type I cells, as judged by freeze-fracture electron microscopy. In contrast to other organisms studied by this technique, no changes in the cell membranes of P. carinii or the host cells could be demonstrated. These data suggest that P. carinii attaches in an unusual manner.

Attachment of Pneumocystis carinii to Type I Alveolar Cells Studied by Freeze-Fracture Electron Microscopy