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The 6-amino-6-deoxy-N -acetylmuramyldipeptides and their 6-acylamino derivatives were shown to be active as adjuvants on the induction of delayed-type hypersensitivity to azobenzenearsonate-N -acetyl-l -tyrosine in guinea pigs. However, 6-acylamino-6-deoxy-N -(acyl)muramyldipeptides were inactive as adjuvants.

infection and immunity

Adjuvant Activity of 6-Amino-6-Deoxy-Muramyldipeptides and Their Acylamino Derivatives on the Induction of Delayed Hypersensitivity to Azobenzenearsonate- N -Acetyl- l -Tyrosine in Guinea Pigs