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New Zealand white rabbits were administered soluble lipoteichoic acid from Streptococcus pyogenes 1-RP41 on alternate days for up to 30 days. An increased incidence of renal cortico-medullary calculi was observed after day 21; the use of fluorescent-labeled anti-teichoic acid antibody located teichoic acid predominantly in the cortical-associated tubules.

Induction of nephrocalcinosis in rabbit kidneys after long-term exposure to a streptococcal teichoic acid