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The M variant of encephalomyocarditis virus is very closely related serologically to five other strains of encephalomyocarditis virus. Despite the serological relationship, these five viruses differ markedly from the M variant in their tissue tropisms and only the M variant infects beta cells of the pancreas, producing diabetes.

Virus-induced diabetes mellitus. V. Biological differences between the M variant and other strains of encephalomyocarditis virus