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The action of trehalose-6, 6′-dimycolate (cord factor) ofMycobacterium tuberculosis to induce site II-specific inhibition of mitochondrial oxidative phosphorylation and to stimulate adenosine triphosphatase activity was neutralized by its specific antibody. The activity was restored after dissociation of cord factor from the immune complex.

Further Study on Neutralization of Biochemical Activity of Cord Factor by Anti-Cord Factor Antibody