English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

Rabbits immunized with purified antigens, choleragen and choleragenoid (cholera exo-enterotoxin and natural toxoid), were found to resist intra-intestinal challenge with a variety of strains of cholera vibrios. The resistance occurred in the absence of a significant antibacterial antibody response. In fact, the antigens were incapable of protecting mice against the septicemic infection of the standard mouse protection test used for bioassay of conventional cholera vaccines. The immunized rabbits did, however, develop a significant antitoxin titer demonstrable by passive hemagglutination, although the presence of antitoxic coproantibody could not be established conclusively. The results suggest the potential value of antitoxic immunity in cholera and are consistent with the existence of only one serological type of cholera exo-enterotoxin.

Antitoxic Immunity in Experimental Cholera: Observations with Purified Antigens and the Ligated Ileal Loop Model