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Porphyromonas gingivalis is considered a keystone pathogen that contributes to the initiation and progression of periodontitis in humans.P. gingivalis has also been detected in human placentas associated with adverse pregnancy outcomes. The spread ofP. gingivalis from the oral cavity to the reproductive tract thus represents a potential mechanism whereby periodontitis can lead to adverse pregnancy outcomes.

Fetal Weight Outcomes in C57BL/6J and C57BL/6NCrl Mice after Oral Colonization with Porphyromonas gingivalis