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The nosocomial pathogenPseudomonas aeruginosa regulates its virulence via a complex quorum sensing network, which, besidesN -acylhomoserine lactones, includes the alkylquinolone signal molecules 2-heptyl-3-hydroxy-4(1H )-quinolone (Pseudomonas quinolone signal [PQS]) and 2-heptyl-4(1H )-quinolone (HHQ).Mycobacteroides abscessus subsp.abscessus , an emerging pathogen, is capable of degrading the PQS and also HHQ. Here, we show that althoughM. abscessus subsp.

infection and immunity

Interference with Pseudomonas aeruginosa Quorum Sensing and Virulence by the Mycobacterial <i>Pseudomonas</i> Quinolone Signal Dioxygenase AqdC in Combination with the <i>N</i> -Acylhomoserine Lactone Lactonase QsdA

Interference with Pseudomonas aeruginosa Quorum Sensing and Virulence by the Mycobacterial Pseudomonas Quinolone Signal Dioxygenase AqdC in Combination with the N -Acylhomoserine Lactone Lactonase QsdA