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Mycobacterium tuberculosis remains a threat to global health, and a more efficacious vaccine is needed to prevent disease caused byM. tuberculosis . We previously reported that the mycobacterial ribosome is a major target of CD4+ T cells in mice immunized with a genetically modifiedMycobacterium smegmatis strain (IKEPLUS) but not in mice immunized withMycobacterium bovis BCG.

Identification of Mycobacterial Ribosomal Proteins as Targets for CD4+T Cells That Enhance Protective Immunity in Tuberculosis

Identification of Mycobacterial Ribosomal Proteins as Targets for CD4⁺T Cells That Enhance Protective Immunity in Tuberculosis