Complete Genome Sequence of Mycobacterium sp. Strain VKM Ac-1817D, Capable of Producing 9α-Hydroxy-androst-4-ene-3,17-dione from Phytosterol
Author(s) -
Victoria Shtratnikova,
Mikhail I. Schelkunov,
Dmitry V. Dovbnya,
Yury A. Pekov,
Eugeny Y. Bragin,
В. В. Ашапкин,
Marina V. Donova
Publication year - 2015
Publication title -
genome announcements
Language(s) - English
Resource type - Journals
ISSN - 2169-8287
DOI - 10.1128/genomea.01447-14
Subject(s) - phytosterol , strain (injury) , whole genome sequencing , genome , biology , ene reaction , mycobacterium , sequence (biology) , chromosome , stereochemistry , gene , genetics , biochemistry , chemistry , bacteria , anatomy
Mycobacterium sp. strain VKM Ac-1817D is capable of converting phytosterol into 9α-hydroxy androst-4-ene-3,17-dione (9-OH-AD), which is a valuable intermediate for the steroid pharmaceutical industry. Here, a complete genome sequence of the strain is reported. The genome consists of a single circular 6,324,222-bp chromosome with a G+C content of 66.2% and encodes approximately 6,000 CDSs, 54 tRNAs, and 6 rRNAs.
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