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We present the 2.05-Mb draft genome sequence ofLactobacillus crispatusJCM5810, a chicken intestinal isolate with the ability to reduceCampylobacter jejunicolonization in chickens. The genome sequence will provide insights on the probiotic mechanisms ofL. crispatusJCM5810.

Draft Genome Sequence of Lactobacillus crispatus JCM5810, Which Can Reduce Campylobacter jejuni Colonization in Chicken Intestine